Individuals Stopping Slimming Medications Put On Pounds at a Quadrupled Rate Compared to Dieters
Fresh analysis indicates that people who come off blockbuster weight-loss injections like Wegovy and Mounjaro can put back on reduced body mass at a significantly accelerated pace than those who stop conventional diet and exercise programs.
Published data in a leading medical journal demonstrates that while obese people can lose a large proportion of their body weight while undergoing treatment, the mass comes back at an average rate of 0.8 kg per month upon discontinuation.
"People buying such drugs must be informed of the danger of fast rebound weight gain when the medication concludes," cautioned lead investigator Dr. Susan Jebb.
Such speed of regain means a reversion to original weight in about 18 months.
Weighing Treatments
The study, which reviewed dozens of trials involving over 9,000 of patients, compared the outcomes of these new drugs with older methods.
Researchers point out that individuals who lose weight through dieting generally see a slower creep back—around 100 grams monthly—once they finish.
The Reason for the Rapid Regain
Nutrition scientists believe the mode of action of the drugs explains the heightened rebound.
These medications imitate a body's own chemical called GLP-1, which moderates appetite.
"Artificially providing the hormone concentrations far above than normal might result in the system to generate a reduced amount of its own natural hormone, and could lessen sensitivity to its actions," said Dr. Adam Collins, a dietetics expert.
"Withdrawal of this hormone supplement means hunger is unsuppressed, making binge eating far more likely."
An Ongoing Condition?
Medical guidelines advise the jabs for people with weight-linked medical conditions, alongside prescribed lifestyle changes.
Professionals say that, considering the high risk of relapse, the therapy should be considered long-term.
This view is reinforced by drug manufacturers, who state that the results "highlight the persistent nature of excess weight," similar to managing conditions like high blood pressure.
User Accounts
Individuals who have come off the jabs report a powerful resurgence of cravings.
"It was like a trigger activating and you're instantly ravenous," recalled a patient.
This challenge is worsened if patients have not developed sustainable lifestyle or habit changes during therapy.
Growing Interest
Figures show that millions of people in the UK have used weight-loss jabs in the past year, with demand continuing to grow.
- Use is more common among women compared to males.
- The middle-aged age group shows the highest level of interest.
- A large proportion obtain the medications through private healthcare rather than the NHS.
In conclusion, experts stress that while the jabs are effective tools for weight loss, they are not a magic cure and maintained weight loss hinges on ongoing lifestyle changes.